Tetrapyrroles and derivatives
Abcam Lactacystin, proteasome inhibitor, 200UG
MW 376.4 Da, Purity >95%. Potent, irreversible, cell-permeable, selective 20S proteasome inhibitor (IC₅₀ = 70 nM). Inhibits cell-cycle progression and induces neurite outgrowth in vitro. Anti-bacterial and antitumor agent. Active in vivo and in vitro.
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC Zinc phthalocyanine (ZnPc) | 14320-04-8 | 98.0% | 577.90 | 500 MG
Zinc phthalocyanine (ZnPc) is a compound utilized in various industrial and biomedical applications. It functions as a catalyst and photoconductor, and shows potential in photodynamic therapy (PDT) and solar-cell applications. It is also capable of photooxidizing cyclohexane.
- Inhibits cancer cell growth in Kyse-140 and OE-33 lines.
- Functions as a photosensitizer, producing reactive oxygen species (ROS) under 694 nm light irradiation.
- Impairs mitochondrial membrane integrity, activates caspase-3, and induces apoptosis in cancer cells.
- Causes long-term damage to the microvascular network in chick chorioallantoic membrane (CAM) models.
- Exhibits antitumor activity in chick chorioallantoic membrane models.
Abcam TC-2403 o x alate, alpha4beta2 nAChR selective agonist, 50MG
MW 252.27 g/mol, Purity >99%. High affinity α4β2 nAChR selective agonist (Ki = 26 nM). Selective for CNS nAChR over muscle, ganglionic or enteric ACh receptors (EC₅₀ = 732 nM in rat thalamic synaptosomes).
The product is subject to the following: Abcam Restricted Use Statement
Strem, An Ascensus Company CAS# 574-93-6. 5g. Phthalocyanine. MFCD00005085
CAS# 574-93-6. 5g. Phthalocyanine. MFCD00005085. Molecular Weight: 514.55. Molecular Formula: C32H18N8. Color/form: blue black pwdr. Strem# 07-1700. http://www.strem.com/catalog/v/07-1700/
Abcam CK 666, Actin polymerization inhibitor, 10MG
MW 296.3 Da, Purity >99%. Potent inhibitor of actin polymerization. Inhibits the Arp2/3 (IC₅₀ = 17 μM), SpArp2/3 (IC₅₀ = 5 μM) and HsArp2/3 complexes (IC₅₀= 4 μM) by preventing a shift into an active conformation.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Pimobendan (Vetmedin), Ca2+ channel sensitizer, 10MG
MW 334.4 Da, Purity >99%. Ca2+ channel sensitizer. Selective PDE3 inhibitor. Inhibits platelet aggregation. Shows antithrombotic, antihypertensive, potent inotropic and vasodilatory effects *in vivo.* Orally active.
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC Cobalt phthalocyanine | 3317-67-7 | 98.0% | 571.46 | 10 G
Cobalt phthalocyanine is identified as a catalyst for redox reactions. It specifically catalyzes the aerobic regeneration of aldehydes and ketones from their corresponding aldoximes and ketoximes. This compound also finds application in the development of electrocatalysts.
- Catalyst of redox reaction
- Catalyzes aerobic regenerations of aldehydes and ketones from aldoximes and ketoximes
- Can be used in the development of electrocatalysts
- Capable of reducing CO2 to CO in water with high activity over a broad pH range from 4 to 14
Abcam Ibotenic acid, e x citoto x ic agonist, 5MG
MW 158.11 Da, Purity >98%. Neuroexcitatory amino acid originally isolated from Amanita species. Neurotoxin often used to model cognitive dysfunctions. NMDA and metabotropic receptor agonist.
The product is subject to the following: Abcam Restricted Use Statement
Abcam AT x -II, NaV channel activator, 50UG
MW 4941 Da, Purity >95%. ATX-II, NaV channel activator. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Flupenthi x ol dihydrochloride, Non-selective dopamine receptor antagonist, 50MG
MW 507.4 Da, Purity >99%. Non-selective antagonist at D₁ and D₂ receptors. Antagonist at dopamine (D₁-D₅), serotonin (5-HT₂), adrenergic (α₁) and histamine (H₁) receptors. Antipsychotic properties in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Pancuronium dibromide, Competitive nicotinic acetylcholine receptor antagonist, 10MG
MW 732.7 Da. Competitive nicotinic acetylcholine receptor (nAChR) antagonist. Displaces acetylcholine (ab120469) from nAChRs (IC₅₀ = 5.5 nM). Neuromuscular blocker and muscle relaxant.
The product is subject to the following: Abcam Restricted Use Statement
Abcam DPDPE, delta opioid receptor agonist, 1MG
MW 645.79 g/mol, Purity >95%. Potent and selective δ opioid receptor agonist (Ki values are 14, >1000 and >1000 nM for opioid receptor subtypes δ, κ and μ, respectively). Centrally active following systemic administration.
The product is subject to the following: Abcam Restricted Use Statement
Abcam SB 216763, GSK3 inhibitor, 10MG
MW 371.2 Da, Purity >98%. Potent and selective GSK3 inhibitor (Ki= 9 nM for GSK-3α). Has little activity against 24 other protein kinases (IC₅₀ > 10 μM). Stimulates glycogen synthesis, gene transcription and is cardio- and neuroprotective.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Endothelin-1 (human, porcine), Vasoconstrictor peptide, 10UG
MW 2491.9 Da. Endothelin-1 (human, porcine), Vasoconstrictor peptide. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement